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Search Results for " bace 1 inhibitor 1 "

14

Compounds

Cat No. Product Name Synonyms Targets
T10449 BACE-1 inhibitor 1 Others
BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).
T11175 Elenbecestat E2609 Beta-Secretase , BACE
Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.
T62995 BACE-1 inhibitor 2
BACE-1 Inhibitor 2 is a potent, CNS-permeable inhibitor of BACE-1, exhibiting an IC50 value of 1.5 nM in enzymatic assays [1].
T3161 β-Secretase inhibitor-STA Beta-Secretase
BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor
T13253 Umibecestat CNP520 BACE
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of al...
T3161L BACE-IN-1 acetate BACE-IN-1 acetate (350228-37-4,Free base) BACE
BACE-IN-1 acetate (BACE-IN-1 acetate (350228-37-4,Free base)) has been used as β-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) inhibitor in BACE1 inhibitor assay. β-Site amyloid precursor protein (APP) c...
T83616 SEW06622 BACE , AChE
SEW06622 is a potent inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer's disease.
T6058 LY2886721 Beta-Secretase , BACE
LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.
T13434 β-Secretase Inhibitor IV Others
β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).
T71383 NB-533
NB-533 is a macrocyclic peptidic BACE-1 inhibitor.
T68278 NB-216
NB-216 is a macrocyclic peptidic BACE-1 inhibitor.
T61206 AChE/BChE/BACE-1-IN-1
AChE/BChE/BACE-1-IN-1 (Compound 4k) is an orally active inhibitor that targets acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It displays IC50 ...
T60691 AChE/BChE/BACE-1-IN-2
AChE/BChE/BACE-1-IN-2 (Compound 4o) exhibits remarkable antioxidant potential and considerable binding capability towards PAS-AChE. AChE/BChE/BACE-1-IN-2 is an orally active AChE, BACE-1 and BChE inhibitor with IC 50 val...
T79299 HAChE-IN-3 Monoamine Oxidase
hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM, demonstrating its ability to cross the blood-brain barrier. This com...
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